DR ANTHONY MELVIN CRASTO,WorldDrugTracker, helping millions, A 90 % paralysed man in action for you, I am suffering from transverse mylitis and bound to a wheel chair, With death on the horizon, nothing will not stop me except God
DR ANTHONY MELVIN CRASTO Ph.D ( ICT, Mumbai) , INDIA 30 Yrs Exp. in the feld of Organic Chemistry. Serving chemists around the world. Helping them with websites on Chemistry.Millions of hits on google, world acclamation from industry, academia, drug authorities for websites, blogs and educational contribution
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Monday 16 April 2012

Cucurbiturils , molecular container that can encapsulate drug molecules and increase the solubility of drugs

cucurbit[n]urils
Giving drug dropouts a new lease of life
Researchers in the US have designed a molecular container that can encapsulate drug molecules and increase their solubility - in one case by almost 3000 times. The new container appears to have low toxicity and can be built from readily available reagents. The finding opens the possibility of re-testing drug candidates that failed because they were insufficiently soluble or improving existing low-solubility drugs.


D Ma et alNat. Chem., 2012, DOI: 10.1038/nchem.1326 





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Wednesday 4 April 2012

Monday 2 April 2012

Imidazole derivatives: A comprehensive survey of their recognition properties


Imidazole derivatives: A comprehensive survey of their recognition properties

Pedro Molina ,  Alberto Tárraga and Francisco Otón

Affiliation Information

1. Departamento de Química Orgánica; Universidad de Murcia; Campus de Espinardo, , Spain

Org. Biomol. Chem., 2012, 10, 1711-1724

DOI:10.1039/C2OB06808G
Due to its amphoteric nature the imidazole ring can function as selective and effective anion and/or cation and even neutral organic molecules receptor system.
Graphical abstract: Imidazole derivatives: A comprehensive survey of their recognition properties